January 23, 2011 ~ Dr. Daniel J. Rader, Director, Preventive Cardiovascular Medicine and Lipid Clinic at the University of Pennsylvania

Dr. Daniel J. Rader

Cooper-McClure Professor of Medicine

Director, Preventive Cardiovascular Medicine and Lipid Clinic

Director, Clinical and Translational Research Center

Associate Director

Institute for Translational Medicine and Therapeutics

University of Pennsylvania School of Medicine

Philadelphia, Pennsylvania

Dr. Rader is the Cooper-McClure Professor of Medicine and is Professor of Pathology and Pharmacology at the University of Pennsylvania School of Medicine. He is Associate Director of Penn’s Institute for Translational Medicine and Therapeutics and Director of the newly created Translational Research Center. He is also the Director of Preventive Cardiovascular Medicine and Lipid Clinic and the Director of the Lipid-Atherosclerosis Research Unit. Dr. Rader’s basic research laboratory focuses on genetic and pharmacologic regulation of lipoprotein metabolism and atherosclerosis, and he directs a translational research program focusing on human genetics of lipid disorders and atherosclerosis and novel approaches to treatment of dyslipidemia and regression of atherosclerosis. He has a particular interest in HDL metabolism, factors and genes involved in its regulation, the causal nature of the relationship of HDL metabolism to atherosclerosis, and novel approaches to targeting HDL metabolism and reverse cholesterol transport in the treatment, prevention, and regression of atherosclerosis.

Dr Rader received his undergraduate degree from Lehigh University and his medical degree from the Medical College of Pennsylvania. He completed an internship and residency in internal medicine at Yale-New Haven Hospital, followed by a year as a Chief Resident. In 1988 he began a fellowship in lipid metabolism at the Molecular Disease Branch of the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and was subsequently appointed to a staff scientist position. He was recruited in 1994 to the University of Pennsylvania.

Dr. Rader is a member of the American Society of Clinical Investigation, a past Established Investigator of the American Heart Association, and a recipient of several awards including the Jeffrey M. Hoeg Award for Basic Science and Clinical Research from the American Heart Association and the Gill Heart Foundation Award for Outstanding Contributions to Cardiovascular Science. He was previously awarded a Burroughs Wellcome Fund Clinical Scientist Award in Translational Research and is a current recipient of a Doris Duke Charitable Foundation Distinguished Clinical Scientist Award, and a Bristol Myers Squibb “Freedom to Discover” Unrestricted Cardiovascular Research Grant. Dr. Rader is an editorial board member of Arteriosclerosis Thrombosis and Vascular Biology, American Journal of Physiology (Endocrinology and Metabolism), Circulation, Circulation Research, Journal of Lipid Research, and Trends in Molecular Medicine. Dr. Rader has authored over 250 peer-reviewed publications, review articles, and book chapters, including chapters on lipoprotein disorders for Harrison’s Principles of Internal Medicine, Topol’s Textbook of Cardiovascular Medicine, and Nelson’s Textbook of Pediatrics. He is a frequently invited speaker nationally and internationally on his basic and translational research in lipoprotein metabolism and atherosclerosis.

Photo Above:  Dr. Daniel J. Rader

Listen to Diabetes Living Today® interview with Dr. Daniel J. Rader

January 23, 2011 ~ Dr. Daniel J. Rader, Cardiologist